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Synthesis and Application of a Clickable Epoxomicin‐Based Probe for Proteasome Activity Analysis

The proteasome is a multisubunit protein complex responsible for the degradation of proteins, making it essential in myriad cellular processes. Several reversible and irreversible peptide substrates inspired by known proteasome inhibitors have been developed to visualize it and monitor its activity;...

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Detalles Bibliográficos
Autores principales: Salazar‐Chaparro, Andres F., Halder, Saayak, Trader, Darci J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354099/
https://www.ncbi.nlm.nih.gov/pubmed/35849029
http://dx.doi.org/10.1002/cpz1.490

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