LOCL-03 INTRATUMORAL DELIVERY OF CONDITIONALLY REPLICATIVE HUMAN ADENOVIRUS 657 EXPRESSING THE IMMUNE CO-STIMULATOR CD40L (CRAD657-CD40L) AS A POTENTIALLY PROMISING TREATMENT FOR RECURRENT PEDIATRIC HIGH GRADE GLIOMA

INTRODUCTION: Malignancies of the central nervous system (CNS) have had largely unchanged survival outcomes despite decades of research. Recently, viral-based therapeutics have shown some benefit for patients with CNS malignancies in early clinical trials. Adenovirus has been demonstrated as safe an...

Descripción completa

Detalles Bibliográficos
Autores principales: Webb, Mason, Khatua, Soumen, Thompson, Jill, Yerovi, Maria Chiriboga, Daniels, David, Schartz, Jonathan, Wongthida, Phonphimon, Hopps, Sidney, Barry, Mary, Barry, Michael, Vile, Richard, Diaz, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354156/
http://dx.doi.org/10.1093/noajnl/vdac078.045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354156/
http://dx.doi.org/10.1093/noajnl/vdac078.045

Ejemplares similares