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BSCI-19 A LENTIVIRAL CRISPR SCREEN FOR EPIGENETIC MODULATORS OF ANTIGENS TARGETED BY CAR T CELLS IN GLIOBLASTOMA

Glioblastoma (GBM) is the most common adult brain tumor and is very difficult to treat. One promising treatment strategy is CAR T cell therapy, in which T cells are used to target and kill cancer cells. However, CAR T cell therapy is not always effective, and more work is needed to realize its poten...

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Detalles Bibliográficos
Autores principales: Jordan Walter, T, Jangde, Nitish, Ayad, Nagi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354158/
http://dx.doi.org/10.1093/noajnl/vdac078.017