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CLRM-02 SINGLE CENTER EXPERIENCE OF DOPAMINE ANTAGONIST ONC-201 FOR RECURRENT H3K27M-MUTANT GLIOBLASTOMA IN ADULTS

OBJECTIVE: To report the single center experience of three adult subjects receiving ONC-201 as part of the ONC018 expanded access clinical trial [NCT03134131]. BACKGROUND: ONC-201 is an oral investigational antagonist against the D2 dopamine receptor that has shown encouraging results for malignant...

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Detalles Bibliográficos
Autores principales: Ekhator, Chukwuyem, Rak, Ramin, Tadipatri, Ramya, Fonkem, Ekokobe, Grewal, Jai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354166/
http://dx.doi.org/10.1093/noajnl/vdac078.023