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LOCL-07 LOCO-REGIONAL INFUSION OF GB-13 (IL13.E13K-PE4E) AS A POTENTIALLY PROMISING TREATMENT FOR RECURRENT HIGH-GRADE GLIOMA

INTRODUCTION: High grade gliomas (HGG) are devastating diseases with largely unchanged survival outcomes despite decades of research. Recent studies suggest the interleukin 13 receptor subunit alpha 2 (IL-13Rα2) is selectively upregulated in up to 80% of HGG, including glioblastoma (GBM) and diffuse...

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Detalles Bibliográficos
Autores principales: Rechberger, Julian, Khatua, Soumen, Campian, Jian, Sarkaria, Jann, Schwartz, Jonathan, Daniels, David, Schrecengost, Randy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354186/
http://dx.doi.org/10.1093/noajnl/vdac078.049