SYST-07 WINDOW-OF-OPPORTUNITY STUDY OF ONC201 IN PEDIATRIC PATIENTS WITH DIFFUSE INTRINSIC PONTINE GLIOMA (DIPG) AND THALAMIC GLIOMA

BACKGROUND: H3 K27M-mutant diffuse midline glioma is a universally fatal malignancy primarily affecting children and young adults; no effective systemic therapy is available. ONC201, a first-in-class imipridone, is an oral, blood-brain barrier penetrating, selective small molecule antagonist of dopa...

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Detalles Bibliográficos
Autores principales: Odia, Yazmin, Koschmann, Carl, Tarapore, Rohinton, Allen, Jeffrey, Hall, Matthew, Daghistani, Doured, Khatib, Ziad, Aguilera, Dolly, MacDonald, Tobey, de Blank, Peter, McGovern, Susan Lynne, Mueller, Sabine, Kline, Cassie, Vitanza, Nicholas, Allen, Joshua E, Zaky, Wafik, Gardner, Sharon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Supplement Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354206/
http://dx.doi.org/10.1093/noajnl/vdac078.086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354206/
http://dx.doi.org/10.1093/noajnl/vdac078.086

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