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LOCL-04 SAFETY AND FEASIBILITY OF RHENIUM-186 NANOLIPOSOME (186RNL) IN LEPTOMENINGEAL METASTASES [LM] PHASE 1/2A DOSE ESCALATION TRIAL

BACKGROUND: LM is a devastating subarachnoid (SA) complication most commonly from breast, lung, melanoma, and gastrointestinal malignancies affecting 110,000 in the USA. Common therapies are radiation and SA/IV chemotherapy. Without treatment, survival is short with limited treatment options and bet...

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Detalles Bibliográficos
Autores principales: Brenner, Andrew, Youssef, Michael, LaFrance, Norman, Hedrick, Marc, Bao, Ande, Phillips, William, Patel, Torel, Weinberg, Jeffrey, Floyd, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354230/
http://dx.doi.org/10.1093/noajnl/vdac078.046