An integrin axis induces IFN-β production in plasmacytoid dendritic cells

Type I interferon (IFN) production by plasmacytoid dendritic cells (pDCs) has been mainly studied in the context of Toll-like receptor (TLR) activation. In the current report, we reveal that, in the absence of TLR activation, the integrin-binding SLAYGLR motif of secreted osteopontin (sOpn) induces...

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Detalles Bibliográficos
Autores principales: Simoes, Davina Camargo Madeira, Paschalidis, Nikolaos, Kourepini, Evangelia, Panoutsakopoulou, Vily
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354318/
https://www.ncbi.nlm.nih.gov/pubmed/35878016
http://dx.doi.org/10.1083/jcb.202102055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354318/
https://www.ncbi.nlm.nih.gov/pubmed/35878016
http://dx.doi.org/10.1083/jcb.202102055

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