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The pleiotropic roles of cGAS–STING signaling in the tumor microenvironment

Cytosolic DNA is prevalent in cells constituting the tumor microenvironment (TME) and can activate the cyclic guanosine monophosphate–adenosine monophosphate synthase (cGAS)–stimulator of interferon genes (STING) innate immune pathway. The initiation, transmission, and execution of the cGAS–STING pa...

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Detalles Bibliográficos
Autores principales: Li, Jun, Bakhoum, Samuel F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354322/
https://www.ncbi.nlm.nih.gov/pubmed/35325182
http://dx.doi.org/10.1093/jmcb/mjac019