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Distinct non-clock-like signatures of the basal cell carcinomas from three sisters with a lethal Gorlin-Goltz syndrome

BACKGROUND: Gorlin-Goltz syndrome (GS) is an inherited disease characterized by predisposition to basal cell carcinomas (BCCs) and various developmental defects, whose numerous disease-causing PTCH1 mutations have been identified in the hedgehog (Hh) signaling pathway. METHODS: In this study, whole...

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Detalles Bibliográficos
Autores principales: Ye, Lihua, Wang, Li, Peng, Kexin, Fang, Ou, Tian, Zhen, Li, Caihua, Fu, Xiaopeng, Chen, Qingdong, Chen, Jia, Luan, Jing, Zhang, Zhenghua, Zhang, Qiaoan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354412/
https://www.ncbi.nlm.nih.gov/pubmed/35932013
http://dx.doi.org/10.1186/s12920-022-01324-7