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NLRP3 downregulation enhances engraftment and functionality of adipose-derived stem cells to alleviate erectile dysfunction in diabetic rats

BACKGROUND: The transplantation of adipose-derived stem cells (ASCs) is a most promising treatment for diabetic erectile dysfunction (DMED). However, the effect of high glucose on the post-transplantation survival of stem cells limits the efficacy of ASCs transplantation. Prolonging the survival tim...

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Detalles Bibliográficos
Autores principales: Luo, Chao, Peng, Yaqian, Zhou, Xiongcai, Fan, Junhong, Chen, Weihong, Zhang, Haibo, Wei, Anyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354456/
https://www.ncbi.nlm.nih.gov/pubmed/35937790
http://dx.doi.org/10.3389/fendo.2022.913296