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Sex-dependent transcription of cardiac electrophysiology and links to acetylation modifiers based on the GTEx database

Development of safer drugs based on epigenetic modifiers, e.g., histone deacetylase inhibitors (HDACi), requires better understanding of their effects on cardiac electrophysiology. Using RNAseq data from the genotype-tissue-expression database (GTEx), we created models that link the abundance of ace...

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Detalles Bibliográficos
Autores principales: Pressler, Michael P., Horvath, Anelia, Entcheva, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354462/
https://www.ncbi.nlm.nih.gov/pubmed/35935618
http://dx.doi.org/10.3389/fcvm.2022.941890