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Structural Connectivity in Down Syndrome and Alzheimer’s Disease

Down syndrome (DS) arises from the triplication of chromosome 21, which leads to an atypical neurodevelopment and the overproduction of the amyloid precursor protein, predisposing to early Alzheimer’s disease (AD). Not surprisingly, trisomy 21 is widely considered a model to study predementia stages...

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Detalles Bibliográficos
Autores principales: Saini, Fedal, Dell’Acqua, Flavio, Strydom, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354601/
https://www.ncbi.nlm.nih.gov/pubmed/35937882
http://dx.doi.org/10.3389/fnins.2022.908413