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Novel interaction interfaces mediate the interaction between the NEIL1 DNA glycosylase and mitochondrial transcription factor A

The maintenance of human mitochondrial DNA (mtDNA) is critical for proper cellular function as damage to mtDNA, if left unrepaired, can lead to a diverse array of pathologies. Of the pathways identified to participate in DNA repair within the mitochondria, base excision repair (BER) is the most exte...

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Detalles Bibliográficos
Autores principales: Sharma, Nidhi, Thompson, Marlo K., Arrington, Jennifer F., Terry, Dava M., Chakravarthy, Srinivas, Prevelige, Peter E., Prakash, Aishwarya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354671/
https://www.ncbi.nlm.nih.gov/pubmed/35938152
http://dx.doi.org/10.3389/fcell.2022.893806