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Human Variation in DNA Repair, Immune Function, and Cancer Risk

DNA damage constantly threatens genome integrity, and DNA repair deficiency is associated with increased cancer risk. An intuitive and widely accepted explanation for this relationship is that unrepaired DNA damage leads to carcinogenesis due to the accumulation of mutations in somatic cells. But DN...

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Detalles Bibliográficos
Autores principales: Cheong, Ana, Nagel, Zachary D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354717/
https://www.ncbi.nlm.nih.gov/pubmed/35935942
http://dx.doi.org/10.3389/fimmu.2022.899574