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Hypersensitivity of Zebrafish htr2b Mutant Embryos to Sertraline Indicates a Role for Serotonin Signaling in Cardiac Development

Selective serotonin reuptake inhibitors (SSRIs) are antidepressants prescribed in 10% of pregnancies in the United States. Maternal use of SSRIs has been linked to an elevated rate of congenital heart defects, but the exact mechanism of pathogenesis is unknown. Previously, we have shown a decrease i...

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Detalles Bibliográficos
Autores principales: Kent, Mitchell E., Hu, Bo, Eggleston, Timothy M., Squires, Ryan S., Zimmerman, Kathy A., Weiss, Robert M., Roghair, Robert D., Lin, Fang, Cornell, Robert A., Haskell, Sarah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354722/
https://www.ncbi.nlm.nih.gov/pubmed/35904815
http://dx.doi.org/10.1097/FJC.0000000000001297