Vicious LQT induced by a combination of factors different from hERG inhibition

Clinically, drug-induced torsades de pointes (TdP) are rare events, whereas the reduction of the human ether-à-go-go-related gene (hERG) current is common. In this study, we aimed to explore the specific factors that contribute to the deterioration of hERG inhibition into malignant ventricular arrhy...

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Detalles Bibliográficos
Autores principales: Xu, Xinping, Yin, Yue, Li, Dayan, Yao, Binwei, Zhao, Li, Wang, Haoyu, Wang, Hui, Dong, Ji, Zhang, Jing, Peng, Ruiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354841/
https://www.ncbi.nlm.nih.gov/pubmed/35935820
http://dx.doi.org/10.3389/fphar.2022.930831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354841/
https://www.ncbi.nlm.nih.gov/pubmed/35935820
http://dx.doi.org/10.3389/fphar.2022.930831

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