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Biotransformation of Abiraterone Into Five Characteristic Metabolites by the Rat Gut Microbiota and Liver Microsomes

It is well known that the role of gut microbiota in drug metabolism, especially in oral difficult absorbable drugs. Understanding the gut microbiota could enable us to understand drugs in new ways. The purpose of the study was to investigate explore the metabolites of the anti-prostate cancer drug A...

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Detalles Bibliográficos
Autores principales: Keranmu, Adili, Yang, Fei-Ya, Wahafu, Wasilijiang, Han, Su-Jun, Yang, Guo-Sheng, Xing, Nian-Zeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354843/
https://www.ncbi.nlm.nih.gov/pubmed/35936674
http://dx.doi.org/10.3389/fonc.2022.890323