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Biotransformation of Abiraterone Into Five Characteristic Metabolites by the Rat Gut Microbiota and Liver Microsomes
It is well known that the role of gut microbiota in drug metabolism, especially in oral difficult absorbable drugs. Understanding the gut microbiota could enable us to understand drugs in new ways. The purpose of the study was to investigate explore the metabolites of the anti-prostate cancer drug A...
Autores principales: | Keranmu, Adili, Yang, Fei-Ya, Wahafu, Wasilijiang, Han, Su-Jun, Yang, Guo-Sheng, Xing, Nian-Zeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354843/ https://www.ncbi.nlm.nih.gov/pubmed/35936674 http://dx.doi.org/10.3389/fonc.2022.890323 |
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