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Intramuscular Inoculation of AS02-Adjuvanted Respiratory Syncytial Virus (RSV) F Subunit Vaccine Shows Better Efficiency and Safety Than Subcutaneous Inoculation in BALB/c Mice

We previously explored a panel of adjuvants formulated with pre-fusion RSV-F protein and found that AS02 may be a promising candidate adjuvant for developing RSV-F subunit vaccines with improved immunogenicity and desired immune response type. In this study, we performed a head-to-head comparison of...

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Detalles Bibliográficos
Autores principales: Bian, Lijun, Zheng, Yu, Guo, Xiaohong, Li, Dongdong, Zhou, Jingying, Jing, Linyao, Chen, Yan, Lu, Jingcai, Zhang, Ke, Jiang, Chunlai, Zhang, Yong, Kong, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354885/
https://www.ncbi.nlm.nih.gov/pubmed/35935960
http://dx.doi.org/10.3389/fimmu.2022.938598