Inhibition of Rac1 in ventral hippocampal excitatory neurons improves social recognition memory and synaptic plasticity

Rac1 is critically involved in the regulation of the actin cytoskeleton, neuronal structure, synaptic plasticity, and memory. Rac1 overactivation is reported in human patients and animal models of Alzheimer’s disease (AD) and contributes to their spatial memory deficits, but whether Rac1 dysregulati...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Haiwang, Ben Zablah, Youssif, Zhang, Haorui, Liu, An, Gugustea, Radu, Lee, Dongju, Luo, Xiao, Meng, Yanghong, Li, Song, Zhou, Changxi, Xin, Tao, Jia, Zhengping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Aging Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354987/
https://www.ncbi.nlm.nih.gov/pubmed/35936771
http://dx.doi.org/10.3389/fnagi.2022.914491

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9354987/
https://www.ncbi.nlm.nih.gov/pubmed/35936771
http://dx.doi.org/10.3389/fnagi.2022.914491

Ejemplares similares