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Serine racemase interaction with N-methyl-D-aspartate receptors antagonist reveals potential alternative target of chronic pain treatment: Molecular docking study

Serine racemase (SR) catalyzes L-serine racemization to activate the N-methyl-D-aspartate receptor (NMDAR). NMDAR activation is associated with the progression of acute-to-chronic neuropathic pain. This study aimed to investigate NMDAR antagonist interactions with SR to obtain potential chronic pain...

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Detalles Bibliográficos
Autores principales: Laksono, Ristiawan Muji, Kalim, Handono, Rohman, Mohammad Saifur, Widodo, Nashi, Ahmad, Muhammad Ramli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355058/
https://www.ncbi.nlm.nih.gov/pubmed/35935687
http://dx.doi.org/10.4103/japtr.japtr_72_22