TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1

Tumor necrosis factor (TNF) receptor-associated periodic syndrome (TRAPS) is an autoinflammatory periodic fever syndrome associated with heterozygous mutations in TNFRSF1A, which encodes TNF receptor type I (TNFR1). Although possible proinflammatory mechanisms have been proposed, most previous studi...

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Detalles Bibliográficos
Autores principales: Akagi, Takahiko, Hiramatsu-Asano, Sumie, Ikeda, Kenta, Hirano, Hiroyasu, Tsuji, Shoko, Yahagi, Ayano, Iseki, Masanori, Matsuyama, Makoto, Mak, Tak W., Nakano, Kazuhisa, Ishihara, Katsuhiko, Morita, Yoshitaka, Mukai, Tomoyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355097/
https://www.ncbi.nlm.nih.gov/pubmed/35936010
http://dx.doi.org/10.3389/fimmu.2022.926175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355097/
https://www.ncbi.nlm.nih.gov/pubmed/35936010
http://dx.doi.org/10.3389/fimmu.2022.926175

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