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Recombinant Listeria ivanovii strain expressing listeriolysin O in place of ivanolysin O might be a potential antigen carrier for vaccine construction

Listeria monocytogenes (LM) induces efficient and specific T-cell immune responses in the host. Listeriolysin O (LLO) is the main virulence protein of LM. LLO helps LM escape from the lysosome. However, the pronounced pathogenicity of LM limits its practical application as a live bacterial vector. L...

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Detalles Bibliográficos
Autores principales: Liang, Qian, Li, Ruidan, Liu, Sijing, Zhang, Yunwen, Tian, Sicheng, Ou, Qian, Chen, Zhaobin, Wang, Chuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355162/
https://www.ncbi.nlm.nih.gov/pubmed/35935244
http://dx.doi.org/10.3389/fmicb.2022.962326