Loss of Monoallelic Expression of IGF2 in the Adult Liver Via Alternative Promoter Usage and Chromatin Reorganization

In mammals, genomic imprinting operates via gene silencing mechanisms. Although conservation of the imprinting mechanism at the H19/IGF2 locus has been generally described in pigs, tissue-specific imprinting at the transcript level, monoallelic-to-biallelic conversion, and spatio-temporal chromatin...

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Detalles Bibliográficos
Autores principales: Ahn, Jinsoo, Lee, Joonbum, Kim, Dong-Hwan, Hwang, In-Sul, Park, Mi-Ryung, Cho, In-Cheol, Hwang, Seongsoo, Lee, Kichoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355166/
https://www.ncbi.nlm.nih.gov/pubmed/35938007
http://dx.doi.org/10.3389/fgene.2022.920641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355166/
https://www.ncbi.nlm.nih.gov/pubmed/35938007
http://dx.doi.org/10.3389/fgene.2022.920641

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