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Palmitate Induces Mitochondrial Energy Metabolism Disorder and Cellular Damage via the PPAR Signaling Pathway in Diabetic Cardiomyopathy

PURPOSE: To establish an in vitro lipotoxicity model with mouse cardiomyocytes (MCMs) and investigate the molecular mechanism of the peroxisome proliferator-activated receptors (PPAR) signaling on mitochondrial energy metabolism disorder and cellular injury in diabetic cardiomyopathy (DCM). METHODS:...

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Detalles Bibliográficos
Autores principales: Zhang, Xianyu, Mao, Min, Zuo, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355343/
https://www.ncbi.nlm.nih.gov/pubmed/35936050
http://dx.doi.org/10.2147/DMSO.S360931