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De Novo Design of Cathepsin B1 Inhibitors as Potential Anti-Schistosomal Agents Using Computational Studies

BACKGROUND: Schistosomiasis is the world’s second most devastating disease after malaria and the leading cause of disease and mortality for more than 200 million people in developing countries. Cysteine proteases, in particular SmCB1, are the most well-researched biological targets for this disorder...

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Detalles Bibliográficos
Autores principales: Alzain, Abdulrahim A, Elbadwi, Fatima A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355347/
https://www.ncbi.nlm.nih.gov/pubmed/35935393
http://dx.doi.org/10.2147/AABC.S361626