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G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis
Neuroinflammation leads to neuronal stress responses that contribute to neuronal dysfunction and loss. However, treatments that stabilize neurons and prevent their destruction are still lacking. Here, we identify the histone methyltransferase G9a as a druggable epigenetic regulator of neuronal vulne...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355351/ https://www.ncbi.nlm.nih.gov/pubmed/35930635 http://dx.doi.org/10.1126/sciadv.abm5500 |