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Selective endocytosis controls slit diaphragm maintenance and dynamics in Drosophila nephrocytes

The kidneys generate about 180 l of primary urine per day by filtration of plasma. An essential part of the filtration barrier is the slit diaphragm, a multiprotein complex containing nephrin as major component. Filter dysfunction typically manifests with proteinuria and mutations in endocytosis reg...

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Detalles Bibliográficos
Autores principales: Lang, Konrad, Milosavljevic, Julian, Heinkele, Helena, Chen, Mengmeng, Gerstner, Lea, Spitz, Dominik, Kayser, Severine, Helmstädter, Martin, Walz, Gerd, Köttgen, Michael, Spracklen, Andrew, Poulton, John, Hermle, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355562/
https://www.ncbi.nlm.nih.gov/pubmed/35876643
http://dx.doi.org/10.7554/eLife.79037