Relationship Between MR Spectroscopy-Detected Glutamatergic Neurometabolites and Changes in Social Behaviors in a Pilot Open-Label Trial of Memantine for Adults With Autism Spectrum Disorder

BACKGROUND: The neurobiology underlying ASD is largely unknown but altered neural excitability/inhibitory ratios have been reported. Memantine is an N-methyl-D-aspartate (NMDA) glutamatergic antagonist studied for the treatment of core ASD symptoms, with mixed results. We examined whether glutamater...

Descripción completa

Detalles Bibliográficos
Autores principales: Nair, Neetu, Hegarty, John Patrick, Cirstea, Carmen Mihaela, Gu, Meng, Appling, Carrina Brooke, Beversdorf, David Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Psychiatry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355704/
https://www.ncbi.nlm.nih.gov/pubmed/35935413
http://dx.doi.org/10.3389/fpsyt.2022.898006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355704/
https://www.ncbi.nlm.nih.gov/pubmed/35935413
http://dx.doi.org/10.3389/fpsyt.2022.898006

Ejemplares similares