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CAR T-Cell-Based gene therapy for cancers: new perspectives, challenges, and clinical developments

Chimeric antigen receptor (CAR)-T cell therapy is a progressive new pillar in immune cell therapy for cancer. It has yielded remarkable clinical responses in patients with B-cell leukemia or lymphoma. Unfortunately, many challenges remain to be addressed to overcome its ineffectiveness in the treatm...

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Detalles Bibliográficos
Autores principales: Jogalekar, Manasi P., Rajendran, Ramya Lakshmi, Khan, Fatima, Dmello, Crismita, Gangadaran, Prakash, Ahn, Byeong-Cheol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355792/
https://www.ncbi.nlm.nih.gov/pubmed/35936003
http://dx.doi.org/10.3389/fimmu.2022.925985