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KIT-Associated Familial GIST Syndrome: Response to Tyrosine Kinase Inhibitors and Implications for Risk Management

Sporadic gastrointestinal stromal tumors (GIST) are rare tumors, with a median age at diagnosis of 60 years. Familial GISTs are very rare and typically associated with earlier onset, with an average age at diagnosis of 48 years. To date, just over 50 familial cases associated with a germline variant...

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Detalles Bibliográficos
Autores principales: Brodey, Alexandra, Kounnis, Valentinos, Hawkes, Lara, Jones, Robin L, McVeigh, Terri P, Cojocaru, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355806/
https://www.ncbi.nlm.nih.gov/pubmed/35791894
http://dx.doi.org/10.1093/oncolo/oyac120