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KIT-Associated Familial GIST Syndrome: Response to Tyrosine Kinase Inhibitors and Implications for Risk Management
Sporadic gastrointestinal stromal tumors (GIST) are rare tumors, with a median age at diagnosis of 60 years. Familial GISTs are very rare and typically associated with earlier onset, with an average age at diagnosis of 48 years. To date, just over 50 familial cases associated with a germline variant...
Autores principales: | Brodey, Alexandra, Kounnis, Valentinos, Hawkes, Lara, Jones, Robin L, McVeigh, Terri P, Cojocaru, Elena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355806/ https://www.ncbi.nlm.nih.gov/pubmed/35791894 http://dx.doi.org/10.1093/oncolo/oyac120 |
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