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Imaging biological macromolecules in thick specimens: The role of inelastic scattering in cryoEM
We investigate potential improvements in using electron cryomicroscopy to image thick specimens with high-resolution phase contrast imaging. In particular, using model experiments, electron scattering theory, Monte Carlo and multislice simulations, we determine the potential for improving electron c...
Autores principales: | Dickerson, Joshua L., Lu, Peng-Han, Hristov, Dilyan, Dunin-Borkowski, Rafal E., Russo, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355893/ https://www.ncbi.nlm.nih.gov/pubmed/35367900 http://dx.doi.org/10.1016/j.ultramic.2022.113510 |
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