Coordination of two kinesin superfamily motor proteins, KIF3A and KIF13A, is essential for pericellular matrix degradation by membrane-type 1 matrix metalloproteinase (MT1-MMP) in cancer cells

MT1-MMP plays a crucial role in promoting the cellular invasion of cancer cells by degrading the extracellular matrix to create a path for migration. During this process, its localization at the leading edge of migrating cells is critical, and it is achieved by targeted transport of MT1-MMP-containi...

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Detalles Bibliográficos
Autores principales: Gifford, Valentina, Woskowicz, Anna, Ito, Noriko, Balint, Stefan, Lagerholm, B. Christopher, Dustin, Michael L., Itoh, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355896/
https://www.ncbi.nlm.nih.gov/pubmed/35122963
http://dx.doi.org/10.1016/j.matbio.2022.01.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355896/
https://www.ncbi.nlm.nih.gov/pubmed/35122963
http://dx.doi.org/10.1016/j.matbio.2022.01.004

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