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BEtarget: A versatile web-based tool to design guide RNAs for base editing in plants

CRISPR-dependent base editors enable direct nucleotide conversion without the introduction of double-strand DNA break or donor DNA template, thus expanding the CRISPR toolbox for genetic manipulation. However, designing guide RNAs (gRNAs) for base editors to enable gene correction or inactivation is...

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Detalles Bibliográficos
Autores principales: Xie, Xianrong, Li, Fuquan, Tan, Xiyu, Zeng, Dongchang, Liu, Weizhi, Zeng, Wanyong, Zhu, Qinlong, Liu, Yao-Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355906/
https://www.ncbi.nlm.nih.gov/pubmed/35983232
http://dx.doi.org/10.1016/j.csbj.2022.07.046