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BEtarget: A versatile web-based tool to design guide RNAs for base editing in plants
CRISPR-dependent base editors enable direct nucleotide conversion without the introduction of double-strand DNA break or donor DNA template, thus expanding the CRISPR toolbox for genetic manipulation. However, designing guide RNAs (gRNAs) for base editors to enable gene correction or inactivation is...
Autores principales: | Xie, Xianrong, Li, Fuquan, Tan, Xiyu, Zeng, Dongchang, Liu, Weizhi, Zeng, Wanyong, Zhu, Qinlong, Liu, Yao-Guang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355906/ https://www.ncbi.nlm.nih.gov/pubmed/35983232 http://dx.doi.org/10.1016/j.csbj.2022.07.046 |
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