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Single-cell transcriptome and cell type-specific molecular pathways of human non-alcoholic steatohepatitis

The aim of this study is to characterize cell type-specific transcriptional signatures in non-alcoholic steatohepatitis (NASH) to improve our understanding of the disease. We performed single-cell RNA sequencing on liver biopsies from 10 patients with NASH. We applied weighted gene co-expression net...

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Detalles Bibliográficos
Autores principales: Fred, Rikard G., Steen Pedersen, Julie, Thompson, Jonatan J., Lee, Julie, Timshel, Pascal N., Stender, Stefan, Opseth Rygg, Marte, Gluud, Lise Lotte, Bjerregaard Kristiansen, Viggo, Bendtsen, Flemming, Hansen, Torben, Pers, Tune H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355943/
https://www.ncbi.nlm.nih.gov/pubmed/35931712
http://dx.doi.org/10.1038/s41598-022-16754-7