Extracellular vesicles enriched in connexin 43 promote a senescent phenotype in bone and synovial cells contributing to osteoarthritis progression

The accumulation of senescent cells is a key characteristic of aging, leading to the progression of age-related diseases such as osteoarthritis (OA). Previous data from our laboratory has demonstrated that high levels of the transmembrane protein connexin 43 (Cx43) are associated with a senescent ph...

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Detalles Bibliográficos
Autores principales: Varela-Eirín, Marta, Carpintero-Fernández, Paula, Guitián-Caamaño, Amanda, Varela-Vázquez, Adrián, García-Yuste, Alejandro, Sánchez-Temprano, Agustín, Bravo-López, Susana B., Yañez-Cabanas, José, Fonseca, Eduardo, Largo, Raquel, Mobasheri, Ali, Caeiro, José Ramón, Mayán, María D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355945/
https://www.ncbi.nlm.nih.gov/pubmed/35931686
http://dx.doi.org/10.1038/s41419-022-05089-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355945/
https://www.ncbi.nlm.nih.gov/pubmed/35931686
http://dx.doi.org/10.1038/s41419-022-05089-w

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