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Mettl3-mediated mRNA m(6)A modification controls postnatal liver development by modulating the transcription factor Hnf4a

Hepatic specification and functional maturation are tightly controlled throughout development. N6-methyladenosine (m(6)A) is the most abundant RNA modification of eukaryotic mRNAs and is involved in various physiological and pathological processes. However, the function of m(6)A in liver development...

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Detalles Bibliográficos
Autores principales: Xu, Yan, Zhou, Zhuowei, Kang, Xinmei, Pan, Lijie, Liu, Chang, Liang, Xiaoqi, Chu, Jiajie, Dong, Shuai, Li, Yanli, Liu, Qiuli, Sun, Yuetong, Yu, Shanshan, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355946/
https://www.ncbi.nlm.nih.gov/pubmed/35931692
http://dx.doi.org/10.1038/s41467-022-32169-4