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Mettl3-mediated mRNA m(6)A modification controls postnatal liver development by modulating the transcription factor Hnf4a
Hepatic specification and functional maturation are tightly controlled throughout development. N6-methyladenosine (m(6)A) is the most abundant RNA modification of eukaryotic mRNAs and is involved in various physiological and pathological processes. However, the function of m(6)A in liver development...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355946/ https://www.ncbi.nlm.nih.gov/pubmed/35931692 http://dx.doi.org/10.1038/s41467-022-32169-4 |