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Histone deacetylase 3 promotes alveolar epithelial–mesenchymal transition and fibroblast migration under hypoxic conditions

Epithelial–mesenchymal transition (EMT), a process by which epithelial cells undergo a phenotypic conversion that leads to myofibroblast formation, plays a crucial role in the progression of idiopathic pulmonary fibrosis (IPF). Recently, it was revealed that hypoxia promotes alveolar EMT and that hi...

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Detalles Bibliográficos
Autores principales: Jeong, Sung Hwan, Son, Eun Suk, Lee, Young Eun, Kyung, Sun Young, Park, Jeong-Woong, Kim, Se-Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355949/
https://www.ncbi.nlm.nih.gov/pubmed/35804191
http://dx.doi.org/10.1038/s12276-022-00796-y