Afadin couples RAS GTPases to the polarity rheostat Scribble

AFDN/Afadin is required for establishment and maintenance of cell-cell contacts and is a unique effector of RAS GTPases. The biological consequences of RAS complex with AFDN are unknown. We used proximity-based proteomics to generate an interaction map for two isoforms of AFDN, identifying the polar...

Descripción completa

Detalles Bibliográficos
Autores principales: Goudreault, Marilyn, Gagné, Valérie, Jo, Chang Hwa, Singh, Swati, Killoran, Ryan C., Gingras, Anne-Claude, Smith, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355967/
https://www.ncbi.nlm.nih.gov/pubmed/35931706
http://dx.doi.org/10.1038/s41467-022-32335-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355967/
https://www.ncbi.nlm.nih.gov/pubmed/35931706
http://dx.doi.org/10.1038/s41467-022-32335-8

Ejemplares similares