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Afadin couples RAS GTPases to the polarity rheostat Scribble

AFDN/Afadin is required for establishment and maintenance of cell-cell contacts and is a unique effector of RAS GTPases. The biological consequences of RAS complex with AFDN are unknown. We used proximity-based proteomics to generate an interaction map for two isoforms of AFDN, identifying the polar...

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Detalles Bibliográficos
Autores principales:	Goudreault, Marilyn, Gagné, Valérie, Jo, Chang Hwa, Singh, Swati, Killoran, Ryan C., Gingras, Anne-Claude, Smith, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355967/ https://www.ncbi.nlm.nih.gov/pubmed/35931706 http://dx.doi.org/10.1038/s41467-022-32335-8

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