The shaping of cancer genomes with the regional impact of mutation processes

Mutation signature analysis has been used to infer the contributions of various DNA mutagenic-repair events in individual cancer genomes. Here, we build a statistical framework using a multinomial distribution to assign individual mutations to their cognate mutation signatures. We applied it to 47 m...

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Detalles Bibliográficos
Autores principales: Lee, Soo-Youn, Wang, Han, Cho, Hae Jin, Xi, Ruibin, Kim, Tae-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355972/
https://www.ncbi.nlm.nih.gov/pubmed/35902761
http://dx.doi.org/10.1038/s12276-022-00808-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355972/
https://www.ncbi.nlm.nih.gov/pubmed/35902761
http://dx.doi.org/10.1038/s12276-022-00808-x

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