Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers

Resistance to platinum-based chemotherapy represents a major clinical challenge for many tumors, including epithelial ovarian cancer. Patients often experience several response-relapse events, until tumors become resistant and life expectancy drops to 12–15 months. Despite improved knowledge of the...

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Detalles Bibliográficos
Autores principales: Van Nyen, Tom, Planque, Mélanie, van Wagensveld, Lilian, Duarte, Joao A. G., Zaal, Esther A., Talebi, Ali, Rossi, Matteo, Körner, Pierre-René, Rizzotto, Lara, Moens, Stijn, De Wispelaere, Wout, Baiden-Amissah, Regina E. M., Sonke, Gabe S., Horlings, Hugo M., Eelen, Guy, Berardi, Emanuele, Swinnen, Johannes V., Berkers, Celia R., Carmeliet, Peter, Lambrechts, Diether, Davidson, Ben, Agami, Reuven, Fendt, Sarah-Maria, Annibali, Daniela, Amant, Frédéric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355973/
https://www.ncbi.nlm.nih.gov/pubmed/35931688
http://dx.doi.org/10.1038/s41467-022-32272-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355973/
https://www.ncbi.nlm.nih.gov/pubmed/35931688
http://dx.doi.org/10.1038/s41467-022-32272-6

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