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Functional human cell-based vascularised cardiac tissue model for biomedical research and testing

Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC) are widely used in in vitro biomedical research and testing. However, fully matured, adult cardiomyocyte characteristics have not been achieved. To improve the maturity and physiological relevance of hiPSC-derived cardiomyocyte...

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Detalles Bibliográficos
Autores principales: Koivisto, Maria, Tolvanen, Tuomas A., Toimela, Tarja, Miinalainen, Ilkka, Kiviaho, Antti, Kesseli, Juha, Nykter, Matti, Eklund, Lauri, Heinonen, Tuula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355975/
https://www.ncbi.nlm.nih.gov/pubmed/35931748
http://dx.doi.org/10.1038/s41598-022-17498-0