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Augmentation of the RNA m6A reader signature is associated with poor survival by enhancing cell proliferation and EMT across cancer types

N(6)-Methyladenosine (m6A) RNA modification plays a critical role in the posttranscriptional regulation of gene expression. Alterations in cellular m6A levels and m6A-related genes have been reported in many cancers, but whether they play oncogenic or tumor-suppressive roles is inconsistent across c...

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Detalles Bibliográficos
Autores principales: Oh, Jaeik, Hwa, Chanwoong, Jang, Dongjun, Shin, Seungjae, Lee, Soo-Jin, Kim, Jiwon, Lee, Sang Eun, Jung, Hae Rim, Oh, Yumi, Jang, Giyong, Kwon, Obin, An, Joon-Yong, Cho, Sung-Yup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9355997/
https://www.ncbi.nlm.nih.gov/pubmed/35794212
http://dx.doi.org/10.1038/s12276-022-00795-z