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PRMT4-mediated arginine methylation promotes tyrosine phosphorylation of VEGFR-2 and regulates filopodia protrusions

Through tightly controlled multilayer mechanisms, vascular endothelial growth factor receptor-2 (VEGFR-2) activation and its downstream signal transduction govern vasculogenesis and pathological angiogenesis, such as tumor angiogenesis. Therefore, it is critical to understand the molecular mechanism...

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Detalles Bibliográficos
Autores principales: Hartsough, Edward, Shelke, Rajani R.J., Amraei, Razie, Aryan, Zahra, Lotfollahzadeh, Saran, Rahimi, Nader
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356023/
https://www.ncbi.nlm.nih.gov/pubmed/35942094
http://dx.doi.org/10.1016/j.isci.2022.104736