Club cells employ regeneration mechanisms during lung tumorigenesis

The high plasticity of lung epithelial cells, has for many years, confounded the correct identification of the cell-of-origin of lung adenocarcinoma (LUAD), one of the deadliest malignancies worldwide. Here, we employ lineage-tracing mouse models to investigate the cell of origin of Eml4-Alk LUAD, a...

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Detalles Bibliográficos
Autores principales: Chen, Yuanyuan, Toth, Reka, Chocarro, Sara, Weichenhan, Dieter, Hey, Joschka, Lutsik, Pavlo, Sawall, Stefan, Stathopoulos, Georgios T., Plass, Christoph, Sotillo, Rocio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356049/
https://www.ncbi.nlm.nih.gov/pubmed/35931677
http://dx.doi.org/10.1038/s41467-022-32052-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356049/
https://www.ncbi.nlm.nih.gov/pubmed/35931677
http://dx.doi.org/10.1038/s41467-022-32052-2

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