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TGFβ-induced changes in membrane curvature influence Ras oncoprotein membrane localization

In the course of cancer progression tumor cells undergo morphological changes that lead to increased motility and invasiveness thus promoting formation of metastases. This process called epithelial to mesenchymal transition (EMT) is triggered by transforming growth factor (TGFβ) but for gaining the...

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Detalles Bibliográficos
Autores principales: Damalas, Alexandros, Vonkova, Ivana, Tutkus, Marijonas, Stamou, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9356053/
https://www.ncbi.nlm.nih.gov/pubmed/35931724
http://dx.doi.org/10.1038/s41598-022-17482-8